Progression from Sustained BK Viruria to Sustained BK Viremia with Immunosuppression Reduction Is Not Associated with Changes in the Noncoding Control Region of the BK Virus Genome

Table 1

Basic demographic data of the patients and sample characteristics.

Patient	Viral load^𝜇			Age	Sex	Type of transplant**	Race	Underlying diagnosis^¶	Onset of viruria	Peak of viruria^𝜇	Onset of viremia	Peak of viremia^𝜇	Mutation*
	Plasma		Urine
	Sample 1	Sample 2
1	5.79	5.29	10.24	59	M	DDA	White	DM1, CIN	Week 5	10.35	Week 9	5.79	P(1), D(0), T(3), I(2)
2	5.46	5.32	11.34	76	M	DDA	African American	DM, HTN	Week 9	11.67	Week 13	5.46	P(4), D(1), T(3), I(0)
3	5.85	5.9	11.13	31	M	DDA	White	PSGN, FSGS	Week 6	11.35	Week 7	5.9	P(2), D(0), T(4), I(0)
4	5.24	5.6	8.32	59	M	LRD	White	HTN	Week 1	8.32	Week 5	5.6	P(0), D(1), T(0), I(0)
5	5.35	5.68	8.79	65	M	DDA	White	HTN	Week 2	10.65	Week 13	5.68	P(2), D(0), T(1), I(0)
6	2.5	2.5	12.02	49	M	DDA	African American	DM2, HTN	Week 1	12.02	Week 4	2.5	P(4), D(0), T(2), I(0)
7	5.53	5.26	No sample	59	M	DDA	White	FSGS	Month 9	10.15	Month 9	5.53	P(1), D(0), T(2), I(0)
8	5	2.5	10.1	49	F	DDA	White	MPGN, SLE	Week 3	8.62	Week 5	5	P(2), D(0), T(2), I(1)
9	5.52	5.36	9.65	48	F	LURD	White	IGAN	Week 1	9.65	Week 5	5.52	P(0), D(1), T(0), I(0)
10	5.76	5.17	10.74	23	F	DDA	White	Wegners	Week 3	5.36	Week 7	5.76	P(0), D(0), T(0), I(5)
11	5.76	5.59	10.67	59	M	DDA	White	HTN	Week 1	10.77	Week 4	6.04	P(0), D(0), T(0), I(0)

*I: insertion; P: transversions; D: deletion; T: transitions.
**LRD: living related transplant; DDA: deceased donor allograft, LURD: living un related donor transplant.
μ: log₁₀
^¶DM2: type 2 Diabetes Mellitus; HTN: hypertension; FSGS: focal segmental glomerulosclerosis; PSGN: post streptococcal glomerulonephritis; IGAN: IgA Nephropathy; MPGN: membranoproliferative glomerulonephritis; SLE: systemic Lupus Erythematosus.