Creatinine-Based Estimations of Kidney Function Are Unreliable in Obese Kidney Donors

Table 2

Performance of estimating equations.

	Bias (mL/min/1.73 m^2)	IQR (mL/min/1.73 m^2)	P30
Normal (BMI < 30) (𝑛=83)
Cockcroft-Gault CrCl	19.7±2.6	35.3	64%
MDRD eGFR	10.2±2.7	35.6	71%
CKD-EPI eGFR	6.5±2.7	35.3	76%
Class I Obesity (BMI 30–35) (𝑛=49)
Cockcroft-Gault CrCl	17.4±3.6	36.5	61%
MDRD eGFR	0.54±3.9	36.0	69%
CKD-EPI eGFR	−3.0±3.9	37.9	69%
Class II/III Obesity (BMI>35) (𝑛=32)
Cockcroft-Gault CrCl	15.9±3.8	31.9	66%
MDRD eGFR	−15.0±4.3	37.3	62%
CKD-EPI eGFR	−19.2±4.1	35.7	56%

Abbreviations: Bias—(measured GF-estimated GFR); IQR—interquartile range; BMI—body mass index (kg/m²); P30—percentage of estimated readings within 30 percent of measured reading; CrCl—creatinine clearance; MDRD—modification of diet in renal disease; CKD-EPI—chronic kidney disease epidemiology collaboration; eGFR—estimated glomerular filtration rate.