Clinical Study
Low CD4/CD8 Ratio in Bronchus-Associated Lymphoid Tissue Is Associated with Lung Allograft Rejection
Table 4
Summary of recent BALT literature.
| Author | Disease state | BALT conclusion |
| Hogg et al., 2004 [2] | COPD | Increased BALT presence with worsening disease severity | Rangel-Moreno et al., 2006 [3] | Rheumatoid lung | Induced BALT presence correlates with increased lung tissue damage | Prop et al., 1985 [4] | Animal lung transplant | Presence of BALT correlates with rejection. Removal of BALT through irradiation of donor abrogates rejection | Hasegawa et al., 1999 [5] | Human lung transplant | BALT presence correlates with minimal to no rejection. BALT may play role in immune tolerance |
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