Influence of Deceased Donor and Pretransplant Recipient Parameters on Early Overall Kidney Graft-Survival in Germany
Table 2
Summary of recipient characteristics used in univariate analyses of graft-survival after isolated kidney transplantation (KTX). For interval-scaled parameters absolute numbers, median, interquartile range, risk ratio (with 95% confidence interval), and values (Cox regression) are shown. For nominal and categorical parameters absolute numbers, proportions, the percentage of graft-failures, and values (log-rank test) are shown. All recipient characteristics investigated are shown in supplementary Table e2.
Basic recipient data
Unit of analysis or factor level
(%)
Median
Interquartile range
Graft-failure (%) or hazard ratio [95% CI]
value
Age
Year
4411
56
46–65
1.028 [1.021–1.035]
<0.001
Weight
kg
4411
75.0
65.0–86.0
1.003 [1.000–1.006]
0.057
Size
cm
4411
172.0
165.0–178.0
0.996 [0.991–1.002]
0.164
Time on dialysis before KTX
Days
4346
2251
1239–2823
1.000 [1.000–1.000]
0.141
Gender
Female
1634
(37.0)
12.7%
0.145
Male
2777
(63.0)
14.3%
Comorbidities before KTX
Diabetes
Not reported
4035
(91.5)
13.4%
<0.001
Reported
376
(8.5)
17.0%
Coronary heart disease
Not reported
3351
(76.0)
11.9%
<0.001
Reported
1060
(24.0)
19.4%
Peripheral artery occlusion disease
Not reported
3908
(88.6)
12.8%
<0.001
Reported
503
(11.4)
21.1%
Immunological risks before KTX
Retransplantation
1st KTX
3779
(85.7)
12.7%
<0.001
2nd KTX
525
(11.9)
19.4%
3rd or more KTX
107
(2.4)
21.5%
Panel reactive antibody (peak value)
0–5%
3511
(79.6)
13.2%
0.020
6–84%
745
(16.9)
15.2%
85–100%
155
(3.5)
20.0%
Panel reactive antibody (last value before KTX)
0–5%
4019
(91.1)
13.3%
0.007
6–84%
345
(7.8)
18.0%
85–100%
47
(1.1)
23.4%
Postoperative course of KTX
Postoperative stay in hospital
Days
4411
21
16–29
1.018 [1.016–1.021]
<0.001
Duration of KTX-operation
Minutes
4411
160
129–198
1.002 [1.000–1.003]
0.009
Postoperative dialysis
Number
4103
0
0–2
1.078 [1.062–1.095]
<0.001
Rejections postoperative
0
3667
(83.1)
11.9%
<0.001
1
635
(14.4)
20.3%
≥2
109
(2.5)
38.5%
Induction therapy at KTX
None
1772
(40.2)
15.0%
0.162
ATG, OKT3, or other
668
(15.1)
15.1%
IL2-receptor antibodies
1971
(44.7)
12.2%
Postoperative complications (worst case scenario in case of multiple counts)
