Influence of Deceased Donor and Pretransplant Recipient Parameters on Early Overall Kidney Graft-Survival in Germany
Table 3
Results of multiple Cox regression analysis concerning graft-survival after isolated kidney transplantation (KTX, ). Data analysis was preceded by a donor-recipient selection process during graft allocation. Only donor and recipient risk factors known before kidney transplantation were considered (all variables listed in Tables e1 and e2 with were considered for selection into the model).
Hazard ratio
95% confidence interval
value
Donor related risk factors (unit of analysis or factor level)
Age (years)
1.020
1.013
1.027
0.000
Size (cm)
0.985
0.977
0.993
0.001
Creatinine at admission (µmol/l)
1.002
1.001
1.004
0.002
Catecholamines before recovery
0.757
0.635
0.901
0.002
Quality of graft (reduced versus good)
1.549
1.217
1.973
0.000
Recipient related risk factors (unit of analysis or factor level)
Age (years)
1.012
1.003
1.021
0.006
Actual PRA (%)
1.007
1.002
1.011
0.006
Retransplantation (yes versus no)
1.850
1.484
2.306
0.000
Cardiovascular disease (yes versus no)
1.436
1.212
1.701
0.000
Induction therapy (none = references)
0.005
(i) Interleukin 2 receptor antibodies
0.741
0.619
0.887
0.001
(ii) Other antibodies (e.g., ATG, OKT3)
0.838
0.665
1.055
0.133
PRA: panel reactive antibodies; catecholamines: norepinephrine, epinephrine, dopamine, or dobutamine; cardiovascular disease: coronary heart disease or peripheral arterial occlusion disease or cerebrovascular insult or diabetes.
