Research Article
Incidence, Characteristics, and Prognosis of Incidentally Discovered Hepatocellular Carcinoma after Liver Transplantation
Table 1
Characteristics of patients.
| | Variables | iHCC () | pdHCC () | Nontumor () | value |
| | Age | 54.0 ± 7.1 | 56.2 ± 7.0 | 49.9 ± 10.9 | <0.001 |
| | Gender (female : male), (%) | 5 : 27 (16 : 84) | 15 : 106 (12 : 88) | 305 : 429 (42 : 58) | <0.001 |
| | Underlying liver disease | | | | | | HCV (yes/no), (%) | 17 : 15 (53 : 47) | 67 : 54 (55 : 45) | 204 : 530 (28 : 72) | <0.001 | | HBV (yes/no), (%) | 2 : 30 (6 : 94) | 28 : 93 (23 : 77) | 34 : 700 (5 : 95) | <0.001 | | Alcoholic liver disease (yes/no), (%) | 14 : 17 (44 : 56) | 37 : 84 (31 : 69) | 216 : 518 (29 : 71) | 0.109 | | Autoimmune liver diseases (yes/no), (%) | 3 : 29 (9 : 91) | 4 : 117 (3 : 97) | 219 : 515 (30 : 70) | <0.001 |
| | MELD at time of transplant | 20.1 ± 6.7 | 14.6 ± 7.4 | 20.5 ± 10.8 | 0.001 |
| | Child-Pugh score | 10.9 ± 2.2 | 8.5 ± 2.6 | 9.96 ± 2.3 | <0.001 |
| | Waiting time (days) | 121.4 ± 152.2 | 203.1 ± 284.2 | 191 ± 176 | 0.039 |
| | Number of lesions | 1.9 ± 1.6 | 2.8 ± 3.8 | — | 0.058 |
| | Maximum diameter | 2.0 ± 1.3 | 3.5 ± 1.9 | — | <0.001 |
| | Milan (within : beyond) | 25 : 8 (78 : 22) | 59 : 52 (49 : 51) | — | 0.021 |
| | Total tumor volume (explant) | 12.2 ± 19.1 | 47.8 ± 108.6 | — | 0.002 |
| | Lowest AFP before transplant | 7.7 ± 6.9 | 98.5 ± 381.7 | — | 0.025 | | Median (range) | 4 (1–28) | 12 (2–3289) |
| | Highest AFP before transplant | 14.2 ± 10.3 | 378.8 ± 1103.2 | — | 0.002 | | Median (range) | 11 (3–41) | 37 (4–8987) |
| | Vascular invasion (no/yes), (%) | 25 : 8 (78 : 22) | 67 : 37 (55 : 45) | — | 0.227 |
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