Research Article

Impact of Early Rejection Treatment on Infection Development in Kidney Transplant Recipients: A Propensity Analysis

Table 2

Infections.

Infection typeCase (n = 169)Control (n = 297)Total (n = 466)

Abscess7 (4.1%)1 (0.3%)8 (1.7%)
Bacteremia14 (8.3%)23 (7.7%)37 (7.9%)
BK nephropathy4 (2.4%)3 (1.0%)7 (1.5%)
BK viremia9 (5.3%)37 (12.5%)46 (9.9%)
Candida3 (1.8%)2 (0.7%)5 (1.1%)
Clostridioides difficile associated disease9 (5.3%)10 (3.4%)19 (4.1%)
CMV disease3 (1.8%)0 (0.0%)3 (0.6%)
CMV viremia24 (14.2%)40 (13.5%)64 (13.7%)
EBV viremia2 (1.2%)6 (2.0%)8 (1.7%)
Herpes simplex (disseminated)1 (0.6%)0 (0.0%)1 (0.2%)
JC polyoma virus0 (0.0%)1 (0.3%)1 (0.2%)
VZV (localized)2 (1.2%)0 (0.0%)2 (0.4%)
Mold infection1 (0.6%)0 (0.0%)1 (0.2%)
Mycobacteria0 (0.0%)1 (0.3%)1 (0.2%)
Nocardia1 (0.6%)4 (1.3%)5 (1.1%)
Other11 (6.5%)24 (8.1%)35 (7.5%)
Pneumocystis jirovecii pneumonia (PJP)0 (0.0%)1 (0.3%)1 (0.2%)
Pneumonia requiring admission6 (3.6%)13 (4.4%)19 (4.1%)
Pulmonary coccidioidomycosis2 (1.2%)1 (0.3%)3 (0.6%)
Pyelonephritis10 (5.9%)9 (3.0%)19 (4.1%)
Symptomatic UTI60 (35.5%)121 (40.8%)181 (38.9%)

All infections identified in this study, with a breakdown between the case and control cohorts. Other infections: parvovirus (4), norovirus (4), coronavirus (not SARS-CoV-2) upper respiratory tract infection (4), rhinovirus (3), parainfluenza virus (2), salmonella gastroenteritis (2), bacillus cereus colitis (2), unspecified colitis (2), influenza virus URI (1), west nile virus meningitis (1), human papilloma virus (1), hepatitis B (1), unspecified osteomyelitis (1), necrotizing fasciitis (1), human metapneumovirus (1), RSV bronchitis (1), orchitis (1), cellulitis (1), legionella pneumonia (1), enteropathogenic E. coli gastroenteritis (1).