Acute Phase Response and Neutrophils : Lymphocyte Ratio in Response to Astaxanthin in Staphylococcal Mice Mastitis Model

Table 1

Therapeutic plan of astaxanthin (AX) in lactating mice challenged with pathogenic Staphylococcus aureus.

Groups	Number of; mice	Treatment	Dose	Frequency	Route	Interval
Group I	6	Normal healthy mice	—	—	—	—
Group II	6	Positive control	—	—	—	—
Group III	6	AX^*	16 mg/kg body weight	Twice daily	Orally	Oral drenching of AX for 5 days PC twice a day
Group IV	6	Antibiotic^**	12.5 mg/kg body weight	Twice daily	Intramuscular	5 days post challenge/twice a day

AX^* was drenched orally after reconstitution in sterile normal saline solution, at the rate of 16 mg/kg body weight 10 days prior to challenge and continued 5 days post challenge.
^**Amoxicillin + sulbactam—via intramuscular route, at 12.5 mg/kg body weight.