Biochemical Effects of Xylazine, Propofol, and Ketamine in West African Dwarf Goats

Table 1

Mean (±SEM) of different biochemical parameters in goats following intravenous administration of different anaesthetic combinations.

Parameter	C	K + X	P + X	P + K	P + K + X
Blood glucose (mg/dL)
0 min	58.06 ± 0.62	57.52 ± 0.91	57.55 ± 1.01	58.10 ± 1.24	58.10 ± 1.24
30 min	60.6 ± 1.93
2 hr	60.75 ± 3.21			57.75 ± 3.30
24 hr	59.66 ± 1.64			61.12 ± 4.20	58.85 ± 1.65
Cortisol (ng/mL)
0 min	33.91 ± 1.38	34.35 ± 2.87	34.08 ± 3.12	31.61 ± 6.17	34.15 ± 5.43
30 min	32.25 ± 4.25	26.31 ± 8.94		21.28 ± 5.26	19.25 ± 4.25
2 hr	32.83 ± 6.31		24.78 ± 5.59
24 hr	35.01 ± 5.36	57.20 ± 14.68		29.54 ± 8.55	28.72 ± 7.53
ALT (iu/L)
0 min	13.90 ± 0.90	15.24 ± 0.57	14.29 ± 0.43	14.82 ± 0.55	15.38 ± 0.72
30 min	14.05 ± 0.42	14.47 ± 1.05	14.36 ± 0.26	13.40 ± 1.38	13.40 ± 1.41
2 hr	14.16 ± 0.59		12.28 ± 1.68	13.47 ± 0.93	15.29 ± 0.27
24 hr	13.98 ± 0.29	13.50 ± 1.96	13.52 ± 2.48
Urea (mg/dL)
0 min	32.73 ± 1.05	35.63 ± 1.72	36.13 ± 1.95	31.31 ± 1.95	33.13 ± 2.73
30 min	36.14 ± 3.93		32.72 ± 1.95	35.15 ± 1.74
2 hr	38.24 ± 3.96	38.37 ± 5.00	38.12 ± 2.09	33.97 ± 1.42	35.61 ± 1.61
24 hr	35.52 ± 2.13	30.84 ± 2.09	34.66 ± 1.73	32.01 ± 2.45	36.28 ± 2.13
Creatinine (mg/dL)
0 min	1.54 ± 0.14	1.72 ± 0.05	1.43 ± 0.96	1.72 ± 0.09	1.68 ± 0.11
30 min	1.59 ± 0.04	1.55 ± 0.02	1.60 ± 0.06	1.60 ± 0.04	1.59 ± 0.06
2 hr	1.60 ± 0.03	1.72 ± 0.05	1.59 ± 0.12	1.65 ± 0.07	1.63 ± 0.03
24 hr	1.46 ± 0.02	1.53 ± 0.04	1.58 ± 0.07	1.57 ± 0.05	1.61 ± 0.08

Data in the same column differ significantly () from the preanaesthetic value (time 0).
^a,bResults with different superscripts within row are significantly () different.
C: control group, K + X: ketamine + xylazine, P + X: propofol + xylazine, P + K: propofol + ketamine, and P + K + X: propofol + ketamine + xylazine.