Research Article
Comparative Pharmacokinetics of Cefquinome (Cobactan 2.5%) following Repeated Intramuscular Administrations in Sheep and Goats
Table 1
Mean (±SE) kinetic parameters of cefquinome following repeated intramuscular injections of 2 mg/kg b.wt. once daily for three consecutive days in sheep and goats.
| ||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
A: zero-time intercept of distribution phase; : first-order absorption rate constant; ": absorption half-life; B: zero-time intercept of elimination phase; : first-order elimination rate constant; : elimination half-life; : maximum serum concentration; : time to peak serum concentration; AUC(0-inf): area under serum concentration-time curve; MRT: mean residence time; IBD: interval between doses. |