Research Article

Mutated KRAS Is an Independent Negative Prognostic Factor for Survival in NSCLC Stage III Disease Treated with High-Dose Radiotherapy

Table 2

Prevalence, and relation to patient characteristics of EGFR mutations, KRAS mutations, and EGFR FISH positivity.

EGFRmutEGFR FISHposKRASmut

= 5 = 7.5%12 = 19.7%19 = 28.8%
Inconclusive283
Median age62 (47–71)62 (43–75)62 (55–73)
Gender F/M60/40%67/33% 58/42%
PS 0/140/60%50/50%48/52%
Stage IIIA/IIIB40/60%17/83%21/79%
Weight loss > 5%20%42%32%
Histology
 Adenocarcinoma40%42%68.5%
 SCC40%42%10.5%
 NSCLC NOS20%16%21%