Myeloid Sarcoma: Clinicopathologic, Cytogenetic, and Outcome Analysis of 21 Adult Patients

Table 1

Characteristics of 21 adult patients with myeloid sarcoma.

No.	Age	Sex	Site	FAB	BMBx	Karyotype
1	43	M	LN/spleen	M2	CML/BP	49, xy, t(9;22), t(12;18), +8, +19, +20
2	37	F	Pleura	M4	AML/M4	46, xx
3	37	F	Pleura	M0	AML/M0	46, xx/47, xy, t(1;3), del5, +8, +3, +4, −12
4	45	M	LN	M0	normal	46, xx/45, xy, t(7;11), t(12;18)
5	23	M	CNS	M2	AML/M2	46, xy, t(9;22)
6	64	M	CNS	M4	AML/M4	46, xy
7	28	F	Vulva	M5	AML/M5	46, xx, t(3;11)(p21;q23)
8	21	F	Lumbar spine-extradural	M4	AML/M4	46, xx, t(8;21), +8, −7
9	72	M	LN	M4	AML/M4	46, xy
10	76	F	LN	M2	normal	Not available
11	43	M	Mediastin-al LN	M5	AML/M5	46, xy, i(1), t(1;1), −2, −5, −6, +8, −11, −12, −15, −17, −19, −22
12	54	M	Skin	M2	AML/M2	46, xy
13	35	M	Head of femur	M4	AML/M4	46, xy
14	77	M	Orbit	M2	normal	46, xy/47, xy, t(1;3), +15
15	63	M	Mediastin-al LN	M2	normal	46, xy/49, xy/50, xy, +2
16	43	M	Pleura	M2	normal	46, xy
17	39	M	Perianal skin	M4	AML/M4	46, xy
18	34	M	CNS	M1	normal	45, xy, t(9;22), −7 *
19	73	M	LN/spleen	M1	normal	47, xy, del5, −3, −7, +22
20	69	F	Pleura	M2	AML/M2	46, xx
21	31	F	Skin mass (groin)	M4	normal	46, xx

Abbreviations: FAB: French-American-British classification; BMBx: bone marrow biopsy; M: male; F: female; LN: lymph node; CNS: central nervous system; CML/BP: chronic myeloid leukemia/blastic phase; AML: acute myeloid leukemia.
*Real-time quantitative polymerase chain reaction (RQ-PCR) test for t(9;22) in the bone marrow was negative.