Clinical Study
Influence of IL10 (G1082A) and TNFα (G308A) Polymorphisms on the Survival of Pediatric Patients with ALL
Table 3
Monitoring of survival according to percentage of allelic frequencies (
).
| | Followup | TNFα A (%) | TNFα G (%) | IL10 A (%) | IL10 G (%) | |
| | 25 months | | | | | | | Survival until | 84.93 | 83.87 | 81.82 | 91.03 | 0.6582 | | Risk estimate | 16.07 | 16.13 | 18.18 | 8.97 | 0.2884 | | Rate (CI95%) | 84.93 (76.72–93.14) | 83.8 (76.40–91.35) | 81.82 (73.20–90.43) | 91.03 (84.68–97.37) | | | 50 months | | | | | | | Survival until | 80.82 | 76.34 | 74.03 | 84.62 | 0.4630 | | Risk estimate | 4.84 | 8.97 | 9.52 | 7.04 | 0.3851 | | Rate (CI95%) | 80.82 (71.79–89.85) | 76.35 (67.71–84.98) | 74.03 (64.23–83.82) | 84.63 (76.61–9262) | | | 75 months | | | | | | | Survival until | 78.08 | 75.27 | 71.43 | 81.84 | 0.5215 | | Risk estimate | 3.39 | 1.41 | 3.51 | 3.28 | 0.9686 | | Rate (CI95%) | 78.08 (68.59–87.57) | 75.27 (66.50–84.04) | 71.43 (61.34–81.52) | 81.84 (73.22–90.46) | | | 100 months | | | | | | | Survival until | 78.08 | 75.27 | 71.43 | 81.84 | 0.5215 | | Risk estimate | 0 | 0 | 0 | 0 | | | Rate (CI95%) | 78.08 (68.59–87.57) | 75.27 (66.50–84.04) | 75.27 (61.34–8152) | 81.84 (73.22–90.46) | | | 126 months | | | | | | | Survival until | 78.08 | 75.27 | 71.43 | 81.84 | 0.5215 | | Risk estimate | 0 | 0 | 0 | 0 | | | Rate (CI95%) | 78.08 (68.59–87.57) | 75.27 (66.50–84.04) | 75.27 (61.34–8152) | 81.84 (73.22–90.46) | |
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Log-rank test: TNFα, = 0.7117, and IL10; = 0.1069; CI95%: confidence interval in 95%.
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