A Novel Cryptic Three-Way Translocation t(2;9;18)(p23.2;p21.3;q21.33) with Deletion of Tumor Suppressor Genes in 9p21.3 and 13q14 in a T-Cell Acute Lymphoblastic Leukemia

<div>aCGH confirmed deletions in 9p21.3 and 13q14.2 (arrows) detected initially by MLPA (result not shown). FISH confirmed presence of these deletions in metaphase and/or interphase. Examples for heterozygote deletions of 9p21.3 and 13q14.2 are depicted; probes specific for the corresponding tumor suppressor genes were labeled in red; centromeric probe for chromosome 9 (D9Z3) was labeled in green.</div>

Leukemia Research and Treatment

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Figure 3: A Novel Cryptic Three-Way Translocation t(2;9;18)(p23.2;p21.3;q21.33) with Deletion of Tumor Suppressor Genes in 9p21.3 and 13q14 in a T-Cell Acute Lymphoblastic Leukemia 

Figure 3 | A Novel Cryptic Three-Way Translocation t(2;9;18)(p23.2;p21.3;q21.33) with Deletion of Tumor Suppressor Genes in 9p21.3 and 13q14 in a T-Cell Acute Lymphoblastic Leukemia 