Review Article

Diagnostic Workup of Small B Cell Lymphomas: A Laboratory Perspective

Figure 1

CLL/SLL. A Wright-Giemsa stained slide of CLL/SLL highlighting the typical small sized lymphocytes with mature chromatin (a). High power 1000) view of a Wright-Giemsa slide of CLL/SLL highlighting atypical morphology with multilobulated nuclei (b). Lymph node involved by CLL/SLL. The lymph node architecture is effaced by an atypical vaguely nodular lymphoid proliferation. Arrow points to a proliferation center (paler area), Hematoxylin-Eosin 10 (c). A high power view (Hematoxylin and Eosin 1000) of the arrowed area in (b), highlighting a proliferation center with scattered large prolymphocytes and paraimmunoblasts with larger nuclei and prominent nucleoli.
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