Biologically Active C<small.letters>o</small.letters>(II) and N<small.letters>i</small.letters>(II) Complexes of
<em>N</em>-(2-Thienylmethylene)-2-Aminothiadiazole

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Metal-Based Drugs 
Volume 8 (2002), Issue 6, Pages 323-327
doi:10.1155/MBD.2002.323

Biologically Active Co(II) and Ni(II) Complexes of N-(2-Thienylmethylene)-2-Aminothiadiazole

Zahid H. Chohan

Department of Chemistry, Islamia University, Bahawalpur, Pakistan

Received 16 April 2002; Accepted 8 May 2002

Abstract

Co(II) and Ni(II) complexes Schiff base, N-(2-thienylmethylene)-2-aminothiadiazole have been prepared and characterized by their physical, spectral and analytical data. The title Schiff-base acts as NNS donor tridentate during the complexation reaction with these metal ions having a composition, [M(L)2]Xn where M=Co(II) or Ni(II), L=, X=NO3− , SO42− , C2O42− or CH3CO2− and n=1 or 2 and show an octahedral geometry. In order to evaluate the effect anions upon chelation, the Schiff-base and its new complexes have been screened for their antibacterial activity against bacterial strains e.g., Escherichia coli, Staphylococcus aureus, and Pseudomonas aeruginosa.