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Molecular Biology International
Volume 2010 (2010), Article ID 740152, 5 pages
doi:10.4061/2010/740152
Research Article

Allele Frequencies of 10 Autosomal STR Loci from Chakma and Tripura Tribal Populations in Bangladesh

Ahmad Ferdous,1 Mohammad Eunus Ali,1 Shafiul Alam,1 Mahamud Hasan,1 Tania Hossain,1 and Sharif Akhteruzzaman2

1National Forensic DNA Profiling Laboratory, Department of Forensic Medicine, Dhaka Medical College, Dhaka 1000, Bangladesh
2Department of Biochemistry and Molecular Biology, University of Dhaka, Dhaka 1000, Bangladesh

Received 14 January 2010; Accepted 28 March 2010

Academic Editor: Alessandro Desideri

Copyright © 2010 Ahmad Ferdous et al. This is an open access article distributed under the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.

Abstract

Allele frequencies of ten autosomal STR loci, D3S1358, vWA, D16S539, D2S1338, D8S1179, D21S11, D18S51, D19S433, TH01, and FGA were investigated in Chakma and Tripura tribal populations of Bangladesh. In both the populations, all loci were in Hardy-Weinberg equilibrium except for FGA locus in Chakma and D21S11 in Tripura. All the loci were highly polymorphic in Chakma population with an observed heterozygosity ( 𝐻 𝑜 ) of > 0.7 and moderately polymorphic in Tripura population ( 𝐻 𝑜 > 0 . 6 ) . However, both the population showed least polymorphism at TH01 locus ( 𝐻 𝑜 < 0 . 6 ) . A comparison between Chakma and Tripura population data revealed statistically significant differences in allele frequency distribution for most of the loci. A similar comparison with the mainstream Bengali population using previously published data from this lab also showed significant difference in allele frequency with these two tribal populations.