Protein Methylation and Stress Granules: Posttranslational Remodeler or Innocent Bystander?

Table 3

Stress granules and neuronal granules share common characteristics and common members.

General	Stress granules	Neuronal granules
Large mRNPs	[19, 60]	[61, 62]
Heterogeneous composition	[63]	[64]
Localized in cytoplasm (both soma and processes)	[63]	[65, 66]
Associated with translational regulation	[67]	[66]
Motile: Exhibit microtubule-dependent movement	[60]	[65]
Remodel in response to exogenous stimuli	[19]	[65]
Specific
Contain FXRP family members	[19, 36]	[65, 66]
Share common RBPs (G3BP, hnRNPA1, hnRNPQ, HuR, staufen, YB1)	[67, 68]	[62, 64]
Contain small ribosomal subunit proteins	[68]	[69]
Contain eukaryotic initiation factors	[67]	[61]

Bracketed numbers are relevant references.