About this Journal Submit a Manuscript Table of Contents
Molecular Biology International
Volume 2011 (2011), Article ID 839872, 8 pages
Review Article

The Role of miRNAs as Key Regulators in the Neoplastic Microenvironment

1Biological, Chemical and Physical Sciences Department, College of Arts and Sciences, Roosevelt University, Chicago, IL 60605, USA
2Department of Cellular and Molecular Pharmacology, The Chicago Medical School, Rosalind Franklin University of Medicine and Science, 3333 Green Bay Road, North Chicago, IL 60064, USA

Received 21 December 2010; Accepted 6 February 2011

Academic Editor: Alessandro Desideri

Copyright © 2011 K. K. Wentz-Hunter and J. A. Potashkin. This is an open access article distributed under the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.

Citations to this Article [10 citations]

The following is the list of published articles that have cited the current article.

  • Indraneel Mittra, Naveen Kumar Nair, and Pradyumna Kumar Mishra, “Nucleic acids in circulation: Are they harmful to the host?,” Journal of Biosciences, vol. 37, no. 2, pp. 301–312, 2012. View at Publisher · View at Google Scholar
  • Alessandro Allegra, Andrea Alonci, Salvatore Campo, Giuseppa Penna, Annamaria Petrungaro, Demetrio Gerace, and Caterina Musolino, “Circulating microRNAs: New biomarkers in diagnosis, prognosis and treatment of cancer (Review),” International Journal Of Oncology, vol. 41, no. 6, pp. 1897–1912, 2012. View at Publisher · View at Google Scholar
  • Tetsuji Suda, Hanako Oba, Hiroyuki Takei, Masafumi Kurosumi, Shin-ichi Hayashi, and Yuri Yamaguchi, “ER-activating ability of breast cancer stromal fibroblasts is regulated independently of alteration of TP53 and PTEN tumor suppressor genes,” Biochemical And Biophysical Research Communications, vol. 428, no. 2, pp. 259–263, 2012. View at Publisher · View at Google Scholar
  • Ping Wu, Luca Agnelli, Brian A. Walker, Katia Todoerti, Marta Lionetti, David C. Johnson, Martin Kaiser, Fabio Mirabella, Christopher Wardell, Walter M. Gregory, Faith E. Davies, Daniel Brewer, Antonino Neri, and Gareth J. Morgan, “Improved risk stratification in myeloma using a microRNA-based classifier,” British Journal of Haematology, vol. 162, no. 3, pp. 348–359, 2013. View at Publisher · View at Google Scholar
  • Raghu Kalluri, and Sonia A. Melo, “miR-29b moulds the tumour microenvironment to repress metastasis,” Nature Cell Biology, vol. 15, no. 2, pp. 139–140, 2013. View at Publisher · View at Google Scholar
  • Paloma del C. Monroig, and George A. Calin, “MicroRNA and Epigenetics: Diagnostic and Therapeutic Opportunities,” Current Pathobiology Reports, vol. 1, no. 1, pp. 43–52, 2013. View at Publisher · View at Google Scholar
  • Qingbao Cheng, Bin Yi, Aihua Wang, and Xiaoqing Jiang, “Exploring and exploiting the fundamental role of microRNAs in tumor pathogenesis,” Oncotargets and Therapy, vol. 6, pp. 1675–1684, 2013. View at Publisher · View at Google Scholar
  • Xiaolei Li, Zhiqiang Wu, Xiaobing Fu, and Weidong Han, “A MicroRNA Component of the Neoplastic Microenvironment: Microregulators with Far-Reaching Impact,” BioMed Research International, vol. 2013, pp. 1–7, 2013. View at Publisher · View at Google Scholar
  • Caroline M. M. Gits, Patricia F. van Kuijk, Jonneke C. W. M. de Rijck, Nikky Muskens, Moniek B. E. Jonkers, Wilfred F. van IJcken, Ron H. J. Mathijssen, Jaap Verweij, Stefan Sleijfer, and Erik A. C. Wiemer, “MicroRNA response to hypoxic stress in soft tissue sarcoma cells: microRNA mediated regulation of HIF3 alpha,” Bmc Cancer, vol. 14, 2014. View at Publisher · View at Google Scholar
  • Yinghan Su, Xiaoya Li, Weidan Ji, Bin Sun, Can Xu, Zhaoshen Li, Guojun Qian, and Changqing Su, “Small molecule with big role: MicroRNAs in cancer metastatic microenvironments,” Cancer Letters, vol. 344, no. 2, pp. 147–156, 2014. View at Publisher · View at Google Scholar