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Molecular Biology International
Volume 2012 (2012), Article ID 153415, 10 pages
TRIM22: A Diverse and Dynamic Antiviral Protein
Department of Microbiology and Immunology, Center for Human Immunology, The University of Western Ontario, London, ON, Canada N6A 5C1
Received 9 January 2012; Accepted 24 February 2012
Academic Editor: Abraham Brass
Copyright © 2012 Clayton J. Hattlmann et al. This is an open access article distributed under the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.
- K. Han, D. I. Lou, and S. L. Sawyer, “Identification of a genomic reservoir for new TRIM genes in primate genomes,” PLoS Genetics, vol. 7, no. 12, Article ID e1002388, 2011.
- R. Rajsbaum, J. P. Stoye, and A. O'Garra, “Type I interferon-dependent and -independent expression of tripartite motif proteins in immune cells,” European Journal of Immunology, vol. 38, no. 3, pp. 619–630, 2008.
- L. Carthagena, A. Bergamaschi, J. M. Luna et al., “Human TRIM gene expression in response to interferons,” Plos one, vol. 4, no. 3, Article ID e4894, 2009.
- S. Hatakeyama, “TRIM proteins and cancer,” Nature Reviews Cancer, vol. 11, pp. 792–804, 2011.
- C. Jefferies, C. Wynne, and R. Higgs, “Antiviral TRIMs: friend or foe in autoimmune and autoinflammatory disease?” Nature Reviews Immunology, vol. 11, no. 9, pp. 617–625, 2011.
- L. M. van der Aa, J. P. Levraud, M. Yahmi et al., “A large new subset of TRIM genes highly diversified by duplication and positive selection in teleost fish,” BMC Biology, vol. 7, article 7, 2009.
- S. L. Sawyer, M. Emerman, and H. S. Malik, “Discordant evolution of the adjacent antiretroviral genes TRIM22 and TRIM5 in mammals,” PLoS Pathogens, vol. 3, no. 12, article e197, 2007.
- S. Nisole, J. P. Stoye, and A. Saïb, “TRIM family proteins: retroviral restriction and antiviral defence,” Nature Reviews Microbiology, vol. 3, no. 10, pp. 799–808, 2005.
- G. Meroni and G. Diez-Roux, “TRIM/RBCC, a novel class of “single protein RING finger” E3 ubiquitin ligases,” Bioessays, vol. 27, no. 11, pp. 1147–1157, 2005.
- Z. Duan, B. Gao, W. Xu, and S. Xiong, “Identification of TRIM22 as a RING finger E3 ubiquitin ligase,” Biochemical and Biophysical Research Communications, vol. 374, no. 3, pp. 502–506, 2008.
- P. Eldin, L. Papon, A. Oteiza, E. Brocchi, T. G. Lawson, and N. Mechti, “TRIM22 E3 ubiquitin ligase activity is required to mediate antiviral activity against encephalomyocarditis virus,” Journal of General Virology, vol. 90, no. 3, pp. 536–545, 2009.
- K. L. Lorick, J. P. Jensen, S. Fang, A. M. Ong, S. Hatakeyama, and A. M. Weissman, “RING fingers mediate ubiquitin-conjugating enzyme (E2)-dependent ubiquitination,” Proceedings of the National Academy of Sciences of the United States of America, vol. 96, no. 20, pp. 11364–11369, 1999.
- B. Gao, Z. Duan, W. Xu, and S. Xiong, “Tripartite motif-containing 22 inhibits the activity of hepatitis b virus core promoter, which is dependent on nuclear-located RING domain,” Hepatology, vol. 50, no. 2, pp. 424–433, 2009.
- S. D. Barr, J. R. Smiley, and F. D. Bushman, “The interferon response inhibits hiv particle production by induction of TRIM22,” Plos Pathogens, vol. 4, no. 2, Article ID e1000007, 2008.
- M. Torok and L. D. Etkin, “Two B or not two B? overview of the rapidly expanding b-box family of proteins,” Differentiation, vol. 67, no. 3, pp. 63–71, 2001.
- K. Ozato, D. M. Shin, T. H. Chang, and H. C. Morse, “TRIM family proteins and their emerging roles in innate immunity,” Nature Reviews Immunology, vol. 8, no. 11, pp. 849–860, 2008.
- X. Li, D. F. Yeung, A. M. Fiegen, and J. Sodroski, “Determinants of the higher order association of the restriction factor TRIM5α and other tripartite motif (TRIM) proteins,” Journal of Biological Chemistry, vol. 286, no. 32, pp. 27959–27970, 2011.
- E. E. Nakayama and T. Shioda, “Anti-retroviral activity of TRIM5α,” Reviews in Medical Virology, vol. 20, no. 2, pp. 77–92, 2010.
- Z. Lukic and E. M. Campbell, “The cell biology of TRIM5α,” Current HIV/AIDS Reports, vol. 9, pp. 73–80, 2012.
- G. Sivaramakrishnan, Y. Sun, R. Rajmohan, and V. C. L. Lin, “B30.2/SPRY domain in tripartite motif-containing 22 is essential for the formation of distinct nuclear bodies,” FEBS Letters, vol. 583, no. 12, pp. 2093–2099, 2009.
- D. A. D. Parry, R. D. B. Fraser, and J. M. Squire, “Fifty years of coiled-coils and α-helical bundles: a close relationship between sequence and structure,” Journal of Structural Biology, vol. 163, no. 3, pp. 258–269, 2008.
- A. Reymond, G. Meroni, A. Fantozzi et al., “The tripartite motif family identifies cell compartments,” EMBO Journal, vol. 20, no. 9, pp. 2140–2151, 2001.
- C. C. Mische, H. Javanbakht, B. Song et al., “Retroviral restriction factor TRIM5α is a TRIMer,” Journal of Virology, vol. 79, no. 22, pp. 14446–14450, 2005.
- A. Bouazzaoui, M. Kreutz, V. Eisert et al., “Stimulated trans-acting factor of 50kDa (Staf50) inhibits HIV-1 replication in human monocyte-derived macrophages,” Virology, vol. 356, no. 1-2, pp. 79–94, 2006.
- A. Kajaste-Rudnitski, S. S. Marelli, C. Pultrone et al., “TRIM22 inhibits HIV-1 transcription independently of its E3 ubiquitin ligase activity, Tat, and NF-κB-responsive long terminal repeat elements,” Journal of Virology, vol. 85, no. 10, pp. 5183–5196, 2011.
- R. Singh, G. Gaiha, L. Werner et al., “Association of TRIM22 with the type 1 interferon response and viral control duRING primary HIV-1 infection,” Journal of Virology, vol. 85, no. 1, pp. 208–216, 2011.
- D. A. Rhodes, B. De Bono, and J. Trowsdale, “Relationship between spry and b30.2 protein domains. evolution of a component of immune defence,” Immunology, vol. 116, no. 4, pp. 411–417, 2005.
- C. Grütter, C. Briand, G. Capitani et al., “Structure of the pryspry-domain: implications for autoinflammatory diseases,” FEBS Letters, vol. 580, no. 1, pp. 99–106, 2006.
- S. Ohkura, M. W. Yap, T. Sheldon, and J. P. Stoye, “All three variable regions of the TRIM5α B30.2 domain can contribute to the specificity of retrovirus restriction,” Journal of Virology, vol. 80, no. 17, pp. 8554–8565, 2006.
- G. Sivaramakrishnan, Y. Sun, S. K. Tan, and V. C. L. Lin, “Dynamic localization of tripartite motif-containing 22 in nuclear and nucleolar bodies,” Experimental Cell Research, vol. 315, no. 8, pp. 1521–1532, 2009.
- C. Tissot, S. A. Taviaux, S. Diriong, and N. Mechti, “Localization of Staf50, a member of the RING finger family, to 11p15 by ruorescence in situ hybridization,” Genomics, vol. 34, no. 1, pp. 151–153, 1996.
- J. Zhang, S. Qin, S. N. J. Sait et al., “The pericentromeric region of human chromosome 11: evidence for a chromosome-specific duplication,” Cytogenetics and Cell Genetics, vol. 94, no. 3-4, pp. 137–141, 2001.
- S. P. Otto and P. Yong, “The evolution of gene duplicates,” Advances in Genetics, vol. 46, pp. 451–483, 2002.
- R. C. Moore and M. D. Purugganan, “The early stages of duplicate gene evolution,” Proceedings of the National Academy of Sciences of the United States of America, vol. 100, no. 26, pp. 15682–15687, 2003.
- B. Conrad and S. E. Antonarakis, “Gene duplication: a drive for phenotypic diversity and cause of human disease,” Annual Review of Genomics and Human Genetics, vol. 8, pp. 17–35, 2007.
- M. Sardiello, S. Cairo, B. Fontanella, A. Ballabio, and G. Meroni, “Genomic analysis of the TRIM family reveals two groups of genes with distinct evolutionary properties,” BMC Evolutionary Biology, vol. 8, no. 1, article 225, 2008.
- S. L. Sawyer, L. I. Wu, M. Emerman, and H. S. Malik, “Positive selection of primate TRIM5α identifies a critical species-specific retroviral restriction domain,” Proceedings of the National Academy of Sciences of the United States of America, vol. 102, no. 8, pp. 2832–2837, 2005.
- M. W. Yap, S. Nisole, and J. P. Stoye, “A single amino acid change in the spry domain of human TRIM5α leads to HIV-1 restriction,” Current Biology, vol. 15, no. 1, pp. 73–78, 2005.
- M. Stremlau, M. Perron, S. Welikala, and J. Sodroski, “Species-specific variation in the B30.2(SPRY) domain of TRIM5α determines the potency of human immunodeficiency virus restriction,” Journal of Virology, vol. 79, no. 5, pp. 3139–3145, 2005.
- A. M. Herr, R. Dressel, and L. Walter, “Different subcellular localisations of TRIM22 suggest species-specific function,” Immunogenetics, vol. 61, no. 4, pp. 271–280, 2009.
- S. Yu, B. Gao, Z. Duan, W. Xu, and S. Xiong, “Identification of tripartite motif-containing 22 (TRIM22) as a novel NF-κB activator,” Biochemical and Biophysical Research Communications, vol. 410, no. 2, pp. 247–251, 2011.
- J. Petersson, P. Lönnbro, A. M. Herr, M. Mörgelin, U. Gullberg, and K. Drott, “The human IFN-inducible p53 target gene TRIM22 colocalizes with the centrosome independently of cell cycle phase,” Experimental Cell Research, vol. 316, no. 4, pp. 568–579, 2010.
- X. Li, B. Gold, C. O'hUigin et al., “Unique features of TRIM5α among closely related human TRIM family members,” Virology, vol. 360, no. 2, pp. 419–433, 2007.
- M. Cioce and A. I. Lamond, “Cajal bodies: a long history of discovery,” Annual Review of Cell and Developmental Biology, vol. 21, pp. 105–131, 2005.
- C. Tissot and N. Mechti, “Molecular cloning of a new interferon-induced factor that represses human immunodeficiency virus type i long terminal repeat expression,” Journal of Biological Chemistry, vol. 270, no. 25, pp. 14891–14898, 1995.
- S. Obad, H. Brunnström, J. Vallon-Christersson, A. Borg, K. Drott, and U. Gullberg, “Staf50 is a novel p53 target gene conferRING reduced clonogenic growth of leukemic U-937 cells,” Oncogene, vol. 23, no. 23, pp. 4050–4059, 2004.
- C. Gongora, C. Tissot, C. Cerdan, and N. Mechti, “The interferon-inducible Staf50 gene is downregulated during t cell costimulation by CD2 and CD28,” Journal of Interferon and Cytokine Research, vol. 20, no. 11, pp. 955–961, 2000.
- B. Gao, Y. Wang, W. Xu, Z. Duan, and S. Xiong, “A 5 extended IFN-stimulating response element is crucial for IFN-γ-induced tripartite motif 22 expression via interaction with ifn regulatory factor-1,” Journal of Immunology, vol. 185, no. 4, pp. 2314–2323, 2010.
- Y. Wang, B. Gao, W. Xu, and S. Xiong, “Brg1 is indispensable for IFN-γ-induced TRIM22 expression, which is dependent on the recruitment of IRF-1,” Biochemical and Biophysical Research Communications, vol. 410, no. 3, pp. 549–554, 2011.
- S. Obad, T. Olofsson, N. Mechti, U. Gullberg, and K. Drott, “Regulation of the interferon-inducible p53 target gene TRIM22 (Staf50) in human t lymphocyte activation,” Journal of Interferon and Cytokine Research, vol. 27, no. 10, pp. 857–864, 2007.
- S. Wieland, R. Thimme, R. H. Purcell, and F. V. Chisari, “Genomic analysis of the host response to hepatitis b virus infection,” Proceedings of the National Academy of Sciences of the United States of America, vol. 101, no. 17, pp. 6669–6674, 2004.
- A. I. Su, J. P. Pezacki, L. Wodicka et al., “Genomic analysis of the host response to hepatitis C virus infection,” Proceedings of the National Academy of Sciences of the United States of America, vol. 99, no. 24, pp. 15669–15674, 2002.
- M. E. Folkers, D. A. Delker, C. I. Maxwell et al., “Encode tiling array analysis identifies differentially expressed annotated and novel capped RNAs in hepatitis C infected liver,” Plos ONE, vol. 6, no. 2, Article ID e14697, 2011.
- X. Y. Mo, W. Ma, Y. Zhang et al., “Microarray analyses of differentially expressed human genes and biological processes in ECV304 cells infected with rubella virus,” Journal of Medical Virology, vol. 79, no. 11, pp. 1783–1791, 2007.
- E. Izmailova, F. M. N. Bertley, Q. Huang et al., “HIV-1 Tat reprograms immature dendritic cells to express chemoattractants for activated T cells and macrophages,” Nature Medicine, vol. 9, no. 2, pp. 191–197, 2003.
- Y. E. Chang and L. A. Laimins, “Microarray analysis identifies interferon-inducible genes and Stat-1 as major transcriptional targets of human papillomavirus type 31,” Journal of Virology, vol. 74, no. 9, pp. 4174–4182, 2000.
- Y. Wang, H. Li, Q. Tang, G. G. Maul, and Y. Yuan, “Kaposi's sarcoma-associated herpesvirus ori-lyt-dependent DNA replication: involvement of host cellular factors,” Journal of Virology, vol. 82, no. 6, pp. 2867–2882, 2008.
- O. Bandman, R. T. Coleman, J. F. LoRING, J. J. Seilhamer, and B. G. Cocks, “Complexity of inflammatory responses in endothelial cells and vascular smooth muscle cells determined by microarray analysis,” Annals of the New York Academy of Sciences, vol. 975, pp. 77–90, 2002.
- Y. J. Deng, Z. X. Huang, C. J. Zhou et al., “Gene profiling involved in immature CD4+ T lymphocyte responsible for systemic lupus erythematosus,” Molecular Immunology, vol. 43, no. 9, pp. 1497–1507, 2006.
- B. Zirn, O. Hartmann, B. Samans et al., “Expression profiling of wilms tumors reveals new candidate genes for different clinical parameters,” International Journal of Cancer, vol. 118, no. 8, pp. 1954–1962, 2006.
- S. Wittmann, C. Wunder, B. Zirn et al., “New prognostic markers revealed by evaluation of genes correlated with clinical parameters in wilms tumors,” Genes Chromosomes and Cancer, vol. 47, no. 5, pp. 386–395, 2008.
- T. X. Liu, J. W. Zhang, J. Tao et al., “Gene expression networks underlying retinoic acid-induced differentiation of acute promyelocytic leukemia cells,” Blood, vol. 96, no. 4, pp. 1496–1504, 2000.
- S. Obad, T. Olofsson, N. Mechti, U. Gullberg, and K. Drott, “Expression of the IFN-inducible p53-target gene TRIM22 is down-regulated duRING erythroid differentiation of human bone marrow,” Leukemia Research, vol. 31, no. 7, pp. 995–1001, 2007.