Probing Retroviral and Retrotransposon Genome Structures: The “SHAPE” of Things to Come
Figure 4
Proposed interconverting structures of the FIV 5′ leader RNA controlling genome dimerization/packaging and translation. For both the long-distance interaction (LDI) (a) and multiple stem-loops (MSL) structures (b), important regulatory sequences have been color-coded. mSD, major splice donor sequence; PBS, primer binding site; DIS, dimer initiation site; Poly(A), poly (A) hairpin; gag AUG, gag initiator methionine codon. See text for fuller details adapted from [31].
