Three-Dimensional Molecular Modeling of a Diverse Range of SC Clan Serine Proteases

Table 3

LOOPP server results for secondary structure matches of Plasmodium falciparum SC serine protease target sequence with known PDB structures.

PDB ID	Secondary structure			Score	Sequence identity (%)	Length (%)
	Helical structure (%)	Extended (%)	Loops/other (%)
Target	36.20	19.00	44.80	—	—	—
1U2E	39.44	18.31	42.25	3.547	19.46	100.00
1J1I	41.80	19.53	38.67	3.484	14.88	97.29
1UKS	40.15	17.84	42.01	3.353	18.35	98.64
1C4X	40.71	16.43	42.86	3.294	14.68	98.64
1CQW	32.98	18.85	48.17	3.207	15.67	85.97
1BN6	32.46	19.37	48.17	3.205	15.67	85.97
1MJS	32.53	18.69	48.79	3.158	18.64	99.55
1BN7	32.98	18.47	43.55	3.042	17.73	99.55
1B6G	33.44	14.75	51.80	3.036	15.84	100.00
1FJ2	29.65	19.91	50.44	2.999	19.71	94.12
1JJF	32.40	20.40	47.20	2.997	16.29	100.00
1EHY	38.43	17.08	44.48	2.937	14.55	99.55
1IMJ	30.73	21.95	47.32	2.933	12.79	92.31
1A85	42.28	15.81	41.91	2.688	17.06	95.48