Retroviral Env Glycoprotein Trafficking and Incorporation into Virions
Figure 2
Proposed models for Env incorporation. (a) The passive incorporation model assumes no interaction between Gag and Env. (b) In the first regulated incorporation model, a direct interaction between the MA domain of Gag and the CT domain of Env occurs during Env incorporation. (c) In the second regulated incorporation model, Gag and Env interact indirectly through a bridging protein (green pentagon) that binds to both proteins. The color scheme for Gag and Env is the same as that in Figure 1. The illustration was adapted from Checkley et al. with permission from Elsevier [23].
