Suppressive Effect of Hydroquinone, a Benzene Metabolite, on In Vitro Inflammatory Responses Mediated by Macrophages, Monocytes, and Lymphocytes
Figure 10
Effect
of thiol-containing compounds on hydroquione-mediated inhibition of NO
production and lymphocyte proliferation. (a) RAW264.7 cells ()
were pretreated with L-cysteine (800 M)
or DTT (100 M) and HQ
(hydroquinone, 25 M) in the presence
or absence of LPS
(2.5 g/mL) for
24 hours. The level of NO was determined by Griess reagent as described in Section
2. (b) Bone marrow-derived cells were
incubated with L-cysteine (800 M) or DTT (100 M) and
hydroquinone (25 M) in the presence or absence of Con A (1 g/mL) for 24 hours. and represent
significant difference as compared to control or HQ-treated group.
