]>Different Effects of Angiotensin Converting Enzyme Inhibitors on Endothelin-1 and Nitric Oxide Balance in Human Vascular Endothelial Cells: Evidence of an Oxidant-Sensitive Pathway : Figure 3
305087.fig.003a
(a)
305087.fig.003b
(b)
Figure 3: Effects of 1 0 8 M captopril (CPT), zofenoprilat (ZOF), lisinopril (LIS), and enalaprilat on TNFα-induced intracellular oxidative stress as evaluated by dichlorofluorescein (DCF, (a)) and glutathione (GSH, (b)) content. (A) 𝑃 < . 0 1 or less versus control and TNF+ZOF and 𝑃 < . 0 0 2 versus TNF+CPT; (B) 𝑃 < . 0 0 0 1 versus control and 𝑃 < . 0 1 versus TNF+ZOF. (C) 𝑃 < . 0 0 0 1 versus TNF, TNF+CPT, TNF+LIS, and TNF+ENA and 𝑃 < . 0 2 versus TNF+ZOF; (D) 𝑃 < . 0 0 0 4 or less versus TNF, TNF+CPT, TNF+LIS, and TNF+ENA.