Inhibitory Effect on Cerebral Inflammatory Response following Traumatic Brain Injury in Rats: A Potential Neuroprotective Mechanism of N-Acetylcysteine
Figure 7
TUNEL immunohistochemistry staining of the injured cortex in SHAM group
(n = 5), TBI group (), and TBI-NAC
group (). (a) SHAM group rats showing few TUNEL apoptotic cells. (b) TBI
group rats showing more TUNEL apoptotic cells stained as brown. (c) TBI-NAC
group rats showing less TUNEL apoptotic cells than TBI group (scar bar, 50 m).
(d) Administration of NAC significantly decreased the apoptotic index in rat injured brain following TBI.
versus SHAM group; versus
TBI group.
