Serum Amyloid A, Procalcitonin, Tumor Necrosis Factor-𝛼, and Interleukin-1𝛽 Levels in Neonatal Late-Onset Sepsis

Table 3

Serum levels of acute phase reactants in newborns with culture-proven sepsis and controls (mean ± SD).

	Patients			Controls
	Day 0	Day 4	Day 8
Procalcitonin (ng/mL)	89.7±30.3^***	50.7±16.8^***	62.7±18.7^****	1.5±0.1
TNF-α (pg/mL)	161.9±78.4^*	86.7±28.6^***	144.8±58.2^**	9.3±4.4
IL-1β (pg/mL)	<1	<1	<1	<1
SAA (ng/mL)	5529.6±375.5	5671.5 ± 367	5643.5±436.2	5461.1±407.5
CRP (mg/dL)	10.4±1.1^***	8.4 ± 1^***	7.3±1.1^***	0.8±0.1

^*𝑃<.05; ^**𝑃<.01; ^***𝑃<.001; ^****𝑃<.0001.