High Levels of Proinflammatory Cytokines, but Not Markers of Tissue Injury, in Unaffected Intestinal Areas from Patients with IBD

Table 4

Correlation analysis of mRNA levels among cytokines and effector molecules in affected areas from UC (Spearman’s correlation rank).

	iNOS	Granzyme B	MMP-3
Proinflammatory cytokines in affected areas only
IL-1𝛽	𝑃<.001	𝑃<.001	N.S.
IL-4	N.S.	𝑃=.048	N.S.
IL-12(p35)	𝑃=.011	𝑃=.018	N.S.
IL-12(p40)	𝑃=.039	𝑃=.020	N.S.
IL-27(p28)	𝑃=.037	N.S.	N.S.
Cytokines in affected and unaffected areas
IFN𝛾	N.S.	N.S.	N.S.
TNF𝛼	N.S.	N.S.	N.S.
IL-6	𝑃=.001	𝑃=.003	N.S.
IL-15	N.S.	𝑃=.021	N.S.
IL-18	N.S.	N.S.	N.S.
IL-23(p19)	N.S.	N.S.	N.S.