Monocyte Chemoattractant Protein 1 is a Prognostic Marker in ANCA-Associated Small Vessel Vasculitis

Table 1

Patient characteristics.

	Remission	Smouldering	Relapse
No. of patients	57	25	17
% female	74	86	62
Age	63 (19–88)	65 (26–82)	60 (26–83)
% MPO/PR3/seroneg	28/63/9	35/47/8	24/62/14
% relapse within 3 M	10	24	—
% develop critical OD	12	32	—
BVAS	0 (0-1)	3 (2–5)	6 (2–11)
P-Cystatin C (mg/l)	1.3 (0.83–4.4)	1.12 (0.84–3.06)	1.22 (0.92–2.2)
P-Creatinine (𝜇 mol/l)	93 (45–498)	81 (52–317)	90 (61–189)
P-CRP (mg/l)	5 (0–57)	9 (0–61)	14 (5–160)
U-PHC (mg/l)	5.6 (0–73.7)	5.7 (0–37.6)	15.9 (5.1–36.1)

MPO = myeloperoxidase-ANCA positive, PR3 = proteinase 3-ANCA positive, seroneg = seronegative, M = months, OD = organ damage, BVAS = Birmingham vasculitis activity score, CRP = C-reactive protein, PHC = protein HC/𝛽2-microglobulin. Age, BVAS, plasma and urine measurements are expressed as “median value (range)”.