Clinical Study

Elevation of High-Mobility Group Protein Box-1 in Serum Correlates with Severity of Acute Intracerebral Hemorrhage

Figure 2

The level of HMGB1 increased significantly in the perihematomal tissue of ICH mice. Data are expressed as mean ± standard deviation. (a) ELISA assay of the changes of HMGB1 levels in the perihematomal tissue of ICH mice. (b) A representative picture of Western blot assay showing the changes of HMGB1 levels in the perihematomal tissue of mice. GAPDH was chosen as the internal control. The changes of HMGB1 were expressed as the ratio of the optical density values of HMGB1 band to the optical density values of GAPDH band. n=15. **versus control; P<.01; ##versus 72 hours; P<.01.
142458.fig.002a
(a)
142458.fig.002b
(b)