Clinical Study

Circulating Cytokine Profiles and Their Relationships with Autoantibodies, Acute Phase Reactants, and Disease Activity in Patients with Rheumatoid Arthritis

Table 1

Demographic, laboratory, and clinical data for the group of RA patients ( 𝑛 = 1 4 0 ).

ParametersQuintiles
Mean ± SDQ1 (p25)Q2 (Median)Q3 (p75)Range

Age (years) 4 8 ± 1 2 41485620–75
Female (%)115 (82.1)
Ethnic origin: Black (%)111 (87.0)
DAS28-CRP 5 . 7 ± 1 . 2 4.85.96.62.3–8.0
HDA ( D A S 2 8 5 . 1 ) (%)63 (45.0)
LDA ( D A S 2 8 3 . 2 & <5.1) (%)62 (44.3)
mHAQ-DI 3 . 2 ± 1 . 6 2.03.54.50.0–6.0
Disease duration (months) 1 2 ± 7 610180–25
SJC 1 0 ± 6 49140–27
X-ray erosions (%)65/121 (53.7)
RF (IU/mL) 4 9 3 ± 8 0 3 401715794–5350
aCCP (U/mL) 6 5 4 ± 6 2 1 8049010822–2431
aMCV (U/mL) 5 9 4 ± 6 7 9 10432677516–3088
CRP (mg/L) 2 3 . 0 ± 2 . 5 5.113.630.60.3–164
SAA (μg/mL) 6 1 ± 1 2 4 516601–882

DAS28: Disease activity score for 28 joints, HDA: High disease activity, LDA: Low disease activity, mHAQ-DI: modified Health assessment questionnaire-disease Index, SJC: Swollen Joint Count, RF: Rheumatoid factor, aCCP: anticyclic citrullinated peptide antibodies, aMCV: Antimodified citrullinated vimentin antibodies, CRP: C-reactive protein, SAA: Serum amyloid A.