Clinical Study

Circulating Cytokine Profiles and Their Relationships with Autoantibodies, Acute Phase Reactants, and Disease Activity in Patients with Rheumatoid Arthritis

Table 2

Demographic, laboratory, and clinical data for the LDA ( 𝑛 = 6 2 ) and HDA ( 𝑛 = 6 3 ) groups of RA patients.

ParametersMDAHDA
QuintilesQuintiles
Mean ± SDQ1 (p25)Q2 (Median)Q3 (p75)RangeMean ± SDQ1 (p25)Q2 (Median)Q3 (p75)Range

Age (years) 4 6 ± 1 0 41455322–68 4 9 ± 1 2 45505720–75
Female (%)47 (75)50 (80)
Ethnicity: Black (%)48 (78)59 (94)
DAS28-CRP 4 . 5 ± 0 . 5 4.34.74.83.3–5.0 6 . 5 ± 0 . 6 6.26.66.95.2–8.7
mHAQ-DI 3 . 3 ± 1 . 7 2.03.64.50.0–6.0 1 . 8 ± 0 . 8 1.32.12.40.0–3.0
Disease duration (months) 1 3 ± 8 711202–24 1 1 ± 8 59182–24
SJC 5 ± 3 3570–15 1 4 ± 6 1013174–28
X-ray erosions (%)28/53 (53)29/57 (51)
RF (IU/mL) 4 8 0 ± 6 8 1 571775594–2860 4 9 1 ± 8 1 2 2117865410–5350
aCCP (U/mL) 6 1 8 ± 6 3 9 5134310012–2026 7 3 4 ± 6 6 7 8959912132–2527
aMCV (U/mL) 5 9 7 ± 7 3 1 9031971020–3028 6 3 8 ± 7 2 7 10833486816–3088
CRP (mg/L) 8 ± 1 0 2581–40 3 6 ± 3 8 1027370–198
SAA (μg/mL) 2 5 ± 4 8 25241–238 9 1 ± 1 5 3 8351241–882

DAS28: Disease activity score for 28 joints, HDA: High disease activity, LDA: Low disease activity, mHAQ-DI: modified Health assessment questionnaire-disease Index, SJC: Swollen Joint Count, RF: Rheumatoid factor, aCCP: anticyclic citrullinated peptide antibodies, aMCV: Antimodified citrullinated vimentin antibodies, CRP: C-reactive protein, SAA: Serum amyloid A.