Clinical Study

Circulating Cytokine Profiles and Their Relationships with Autoantibodies, Acute Phase Reactants, and Disease Activity in Patients with Rheumatoid Arthritis

Table 4

Circulating cytokine data for the MDA ( 𝑛 = 6 2 ) and HDA ( 𝑛 = 6 3 ) groups of RA patients..

MDAHDA
CytokinesQuintilesQuintiles
Mean±SDQ1 (p25)Q2 (Median)Q3 (p75)RangeMean±SDQ1 (p25)Q2 (Median)Q3 (p75)Range

IL-1β 1 9 ± 2 9 34260–122 3 0 ± 6 0 15170–269
IL-1Ra 2 9 1 ± 4 9 5 28732660–2994 4 2 9 ± 9 7 3 26902520–5012
IL-2 3 3 ± 8 8 00310–516 3 3 ± 6 8 00270–297
IL-4 3 3 ± 7 5 05150–361 2 0 ± 0 . 4 6 03110–254
IL-6 5 1 ± 7 9 616600–309 7 3 ± 1 2 0 1127860–792
IL-7 1 6 0 ± 4 7 6 521950–3324 2 8 2 ± 9 5 4 723780–6852
IL-8 5 4 ± 1 6 7 59180–997 6 1 2 ± 4 6 2 0 811230–36699
IL-10 3 5 ± 8 2 311220–472 5 1 ± 1 7 8 610270–1172
IL-12 1 7 2 ± 4 0 1 211481–226 1 1 7 ± 4 0 7 313641–3105
IL-17A 8 ± 3 7 0000–229 3 ± 9 0000–46
IFN-γ 5 8 5 ± 1 4 4 4 3483500–7541 5 2 7 ± 1 3 3 0 0271600–6431
G-CSF 1 8 1 ± 4 6 1 116550–2285 1 7 9 ± 4 2 3 07640–1664
GM-GSF 8 7 ± 2 1 1 00240–1048 1 0 1 ± 2 3 6 00410–978
TNF 1 6 1 ± 4 5 2 511541–2952 1 3 1 ± 3 9 2 512691–2665
VEGF 4 7 5 ± 7 6 9 541395130–3582 4 1 9 ± 5 0 2 701985349–2196
CCL2 6 9 ± 8 5 0411090–417 1 1 2 ± 2 7 6 14551030–1771
CCL4 1 1 7 ± 6 4 689516327–291 1 5 9 ± 1 1 6 8911919932–643

Values in pg/mL.