Role of Meconium and Hypoxia in Meconium Aspiration-Induced Lung Injury in Neonatal Rabbits
Table 1
(a) Total lung lavage cell count after exposure to saline, meconium, and milk.
Time
Saline (total lavage cells)
Meconium (total lavage cells)
Milk (total lavage cells)
0 hours
4 hours
8 hours
24 hours
*
versus 0 hrs Meconium group demonstrated a lower total lavage cell number compared to saline and milk groups. At 8 and 24 hrs after meconium instillation, the decrease of cells is significantly lower () than baseline.
(b) Total lung lavage cell count after exposure to hypoxia and hyperoxia.
Time
Hypoxia group (total lavage cells)
Hyperoxia group (total lavage cells)
15 min
Lavage from hypoxic animals contained lower number of total cells, compared to hyperoxia group.
