Insulin Resistance, Inflammation, and Obesity: Role of Monocyte Chemoattractant Protein-1 (orCCL2) in the Regulation of Metabolism
Figure 2
Inflammatory and metabolic responses may be interpreted as a response to cellular stress. Cells detect and react to stress in their environment. The endoplasmic reticulum is a principal contributor due to its central role in integrating multiple metabolic signals critical for cellular homeostasis.