Inhibition of Toll-Like Receptor 2-Mediated Interleukin-8 Production in Cystic Fibrosis Airway Epithelial Cells via the 𝛼7-Nicotinic Acetylcholine Receptor

Figure 5

Nicotine does not increase CFTE cell death but increases cell survival at certain concentrations. CFTE29o- cells ($1\times {10}^5$/mL) were left untreated or stimulated with increasing doses of nicotine (in triplicate) for 24 hours. Cell proliferation was quantified and values are expressed as a percentage change from the untreated cells $({}^{*}P\le .05)$.