Clinical Study
Relevance of Serum Leptin and Leptin-Receptor Concentrations in Critically Ill Patients
Table 1
Characteristics of the study population.
| | Parameter | All ICU patients | Sepsis | Nonsepsis |
| | Number | 137 | 95 | 42 | | Sex (number male/number female) | 85/52 | 59/36 | 26/16 | | Sex (% male/female) | 62/38 | 62/38 | 62/38 | | Age median (years) (range) | 63 (18–81) | 64 (20–81) | 60 (18–79) | | BMI median (kg/m²) (range) | 25.4 (15.3–59.5) | 25.65 (15.3–59.5) | 24.9 (17.5–37.4) | | Days at ICU median (range) | 8 (1–137) | 10 (1–137) | 6 (1–45) | | Days in hospital median (range) | 25 (2–151) | 30 (2–151) | 14 (2–85) | | Death at ICU (%) | 41 (29.9) | 30 (31.6) | 11 (26.2) | | Death during follow-up (%) | 71 (51.8) | 49 (51.6) | 22 (52.4) | | C-reactive protein median (mg/dL) (range) | 112 (5–230) | 167 (5–230) | 14.5 (5–164) | | Procalcitonin median (g/L) (range) | 0.9 (0.1–207.5) | 2.2 (0.1–207.5) | 0.2 (0.1–36.5) | | IL-6 median (ng/L) (range) | 110 (2–1000) | 170 (7.7–1000) | 40.5 (2–1000) | | IL-10 median (ng/L) (range) | 16 (5–1500) | 20 (5–1500) | 5.9 (5–750) | | Protein median (g/L) (range) | 52.5 (21–77) | 52 (21–77) | 55.5 (31–73) | | Prothrombin time median (%) (range) | 73 (11–100) | 75 (11–100) | 69 (13–100) | | Creatinine median (mg/dL) (range) | 1.6 (0.1–13.1) | 1.9 (0.1–10.7) | 1.2 (0.3–13.1) | | Cystatin C median (mg/L) (range) | 1.76 (0.41–7.30) | 1.89 (0.41–6.33) | 1.34 (0.41–7.30) | | Glucose median (mg/dL) (range) | 134 (47–663) | 126 (47–299) | 155 (65–663) | | Insulin median (mU/L) (range) | 9.8 (0.2–1000) | 7.7 (0.2–438.0) | 25.0 (0.2–1000) | | C-peptide median (nmol/L) (range) | 1.66 (0–13.0) | 1.56 (0–13.0) | 2.01 (0–11.6) | | APACHE II score median (range) | 14 (0–31) | 14 (0–31) | 15 (0–28) | | SAPS-2 score median (range) | 43 (0–80) | 43 (0–79) | 41.5 (13–80) |
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BMI: body mass index; IL: interleukin; ICU: intensive care unit; APACHE: Acute Physiology and Chronic Health Evaluation.
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