Role of Bone Marrow-Derived Monocytes/Macrophages in the Repair of Mucosal Damage Caused by Irradiation and/or Anticancer Drugs in Colitis Model
Figure 4
Effect of 5-FU treatment on the AA-induced mucosal damage. (a) 5-FU induced leukocytopenia and bone marrow suppression on day 7. Values represent mean ± SEM. Data were analyzed using the Welch’s -test. **, Saline versus 5-FU. (b) Mucosal damage was induced by AA treatment on day 0 and injected 5-FU (100 mg/kg) on the same day. 5-FU treatment exacerbated the mucosal damage and delayed mucosal healing on day 7 like the simultaneous irradiation in Figure 2(b). Values represent mean ± SEM. Data were analyzed using the Tukey method. *, AA versus AA + 5-FU.
