Expression of TLR4-MyD88 and NF-𝜅B in the Iris during Endotoxin-Induced Uveitis

Figure 2

(a) The clinical score of EIU at different time (Data were expressed as means ± SD): the intensity of the anterior segment inflammation was evaluated at 0$~$12 h inflammation reached a maximum at 24 h inflammation subsided gradually after 24 h. (b) Expression of TLR4, MyD88 and NF-$\kappa$B p65 during iris at different time (Data were expressed as means ± SD): positive cells gradually increased at 0$~$24 h. Expression of MyD88 at 48 h compared with 24 h was no significant difference ($P=.940$). Expression of TLR4 and NF-$\kappa$B p65 at 48 h compared with 24 h was significant difference ($P=.049\text{,}$$P=.000$). Expression of TLR4 and NF-$\kappa$B p65 declined at 72 h.

(a)

(b)