Research Article

Expression of TLR4-MyD88 and NF- B in the Iris during Endotoxin-Induced Uveitis

Table 1

Clinical scoring of endotoxin-induced uveitis and density of immunopositive cells in the rat iris.

Time
(after LPS injection)
clinical grade (mean±SDn=10)TLR4+
(Cell/mm2, n=10)
MyD88+ (Cell/mm2  n=10)NF-κB p65+ (Cell/mm2  n=10)

0 h0±00±00±00±0
12 h2.2±0.4167.9±61.5154.3±41.6220.0±54.6
24 h4.0±0780.0±191.91040.7±209.2402.1±55.4
48 h3.1±0.3917.9±194.61034.6±267.3807.9±177.2
72 h1.7±0.5573.6±113.3650.8±97.8150±57.9