Inflammatory Role of Toll-Like Receptors in Human and Murine Adipose Tissue

Figure 4

Induction of genes coding for IL6, CCL2, CCL5, CCL11, NOS2, and PTGS2 was measured by qPCR in preadipocytes (a) or in differentiated 3T3L1 (b) after 4 hours stimulation with 1 ng/mL Pam3CSK4 in the absence (white) or presence of a blocking antibody (25 $\mu$g/mL; grey) or an isotypic control (25 $\mu$g/mL; black). Mann-Whitney analysis was performed between values obtained in absence or presence of antibodies (${}^{*}\text{,}$$P<.05$).

(a)

(b)