Research Article

Modulation of NK Cell Autocrine-Induced Eosinophil Chemotaxis by Interleukin-15 and Vitamin D3: A Possible NK-Eosinophil Crosstalk via IL-8 in the Pathophysiology of Allergic Rhinitis

Table 1

Amount of IL-8 recovered in supernatants of NK cells after 72 h culture period.

StimulantIL-8 (Pg/mL) in NK cells supernatants

RPMI88.6 ± 21.5
IL-15 (1 ng/mL)178.9 ± 23.6
Vit D3 (10–6 M)59.2 ± 16.3***
SB203580 (10–5 M)15 ± 0.5***
IL-15 (1 ng/mL) + SB203580 (10–5 M)54.75***

Results are ±SEM of 4–8 independent experiments. Asterisks indicate by paired -test.