Antiasthmatic Effects of Hesperidin, a Potential Th2 Cytokine Antagonist, in a Mouse Model of Allergic Asthma
Figure 3
((a), (b), (c)) Effect of HPN on Th2 cytokines (IL-5, IL-13), Th17 cytokine (IL-17), eotaxin in BALF, and OVA-specific IgE in serum. (d) Immunomodulatory effects of HPN on OVA-specific Th1/Th2 cytokines production in spleen cells (described in Section 2). Results are expressed the mean ± S.E (). Statistical significance between control and treatment groups was assessed by ANOVA (*, **, significant increase; #). : normal BALB/c mice, CT: Ovalbumin inhalation+vehicle, formoterol: OVA + formoterol (1 mg/kg), OVA + HPN (5, 1 mg/kg).
