A Role of Fluoride on Free Radical Generation and Oxidative Stress in BV-2 Microglia Cells

<table>Effects of fluoride on <svg height="17.65" id="M30" style="vertical-align:-3.276pt" version="1.1" viewbox="0 0 32.987499 17.65" width="32.987499" xmlns="http://www.w3.org/2000/svg" xmlns:xlink="http://www.w3.org/1999/xlink">
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</svg> production (a) and NT concentrations (b) in microglial BV-2 cells. BV-2cells were treated with various concentrations of NaF (1, 10, and 50 mg/L) for a 24 h incubation period, and DHE fluorescence intensity was measured by flow cytometry for <svg height="17.65" id="M31" style="vertical-align:-3.276pt" version="1.1" viewbox="0 0 32.987499 17.65" width="32.987499" xmlns="http://www.w3.org/2000/svg" xmlns:xlink="http://www.w3.org/1999/xlink">
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</svg> content and DHE fluorescence intensity fold of control was analyzed. Intracellular NT concentrations were measured by ELISA. Bars were presented as mean ± SD. *<svg height="11.375" id="M32" style="vertical-align:-0.1638pt" version="1.1" viewbox="0 0 58.712502 11.375" width="58.712502" xmlns="http://www.w3.org/2000/svg" xmlns:xlink="http://www.w3.org/1999/xlink">
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</svg> and <sup>#</sup><svg height="11.375" id="M33" style="vertical-align:-0.1638pt" version="1.1" viewbox="0 0 58.712502 11.375" width="58.712502" xmlns="http://www.w3.org/2000/svg" xmlns:xlink="http://www.w3.org/1999/xlink">
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</svg> compared to the control group.</table>

Mediators of Inflammation

fig5

Figure 5

Figure 5: A Role of Fluoride on Free Radical Generation and Oxidative Stress in BV-2 Microglia Cells 