Involvement of the Ubiquitin-Proteasome System in the Formation of Experimental Postsurgical Peritoneal Adhesions

Figure 3

Levels (ng/mg tissue) of ubiquitin and 20S proteasome in the tissues from rats during peritoneal adhesions development. At time 0, 5, and 10 in the group treated with bortezomib by intravenous injection (0.05 mg/kg) given 1 hour before surgery, a second injection was given 1 hour after the surgical procedure (total dose of 0.1 mg/kg) and in the control group. The differences from day 0 are considered with *𝑃<0.01, and the differences from the control group at the same day are considered as °𝑃<0.01.

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