L-Arginine and Asymmetric Dimethylarginine Are Early Predictors for Survival in Septic Patients with Acute Liver Failure
Table 3
Routine markers for liver impairment in surviving and nonsurviving septic patients with an ALF.
Parameters
Units
Routine markers for liver impairment in surviving and nonsurviving septic patients with an ALF.
Timepoints
Onset
24 h
4 d
7 d
14 d
28 d
ALF:
Survivors at Day 28 (italic parts, ) versus nonsurvivors at Day 28 (bold parts, )
ASAT
[U/L]
48.0; 23.0–132.0
.072
51.0; 25.5–164.0
.072
62.0; 55.8–89.3
n.s.
82.5; 47.8–115.3
n.s.
52.0; 38.5–69.8
n.s.
44.0; 39.5–99.5
Ø
534.0; 56.0–1798.5
438.0; 100.0–1653.0
113.0; 71.0–621.0
505.5; 267.8–743.3
52.0; 43.0–61.0
Ø
ALAT
[U/L]
21.0; 13.8–43.5
*
20.0; 14.0–47.8
.054
30.5; 19.8–39.5
n.s.
23.5; 18.5–38.0
n.s.
26.5; 18.5–45.0
n.s.
31.0; 19.0–72.0
Ø
266.0; 45.5–365.0
298.0; 50.0–846.0
125.0; 74.5–290.5
211.0; 116.5–305.5
49.5; 36.8–62.3
Ø
LDH
[U/L]
203.0; 190.8–255.5
*
188.5; 179.5–230.5
**
229.0; 173.8–264.3
n.s.
237.5; 187.5–327.8
n.s.
216.0; 196.3–232.5
n.s.
216.0; 184.0–262.5
Ø
453.0; 271.0–1302.5
339.0; 300.0–1267.0
315.0; 279.0–968.0
664.0; 416.5–911.5
236.0; 233.0–239.0
Ø
Total bilirubine
[mg/dL]
4.0; 1.9–4.5
.054
3.1; 2.1–4.7
.094
3.8; 2.9–7.8
n.s.
4.7; 2.9–10.0
n.s.
5.8; 3.4–13.1
n.s.
6.4; 4.2–14.7
Ø
5.8; 4.8–7.5
9.0; 4.2–9.6
2.4; 2.3–9.2
2.3; 2.2–2.5
4.8; 3.3–6.2
Ø
Data are presented by median and interquartile range (Q1–Q3). Concerning symbolism and higher orders of significance: : *, : **, : ***, n.s.: not statistically significant, Ø: no data available. Abbreviations: ALF, acute liver failure; ASAT, aspartat amino transferase; ALAT, alanine amino transferase; LDH, lactate dehydrogenase.
