Review Article

Thrombopoietin as Biomarker and Mediator of Cardiovascular Damage in Critical Diseases

Figure 1

Schematic representation of TPO/c-Mpl functions in vascular system. PLTs = platelets; ECs = endothelial cells; MØ = monocytes; PAF = platelet-activating factor; IL-8 = interleukin-8; HUVECs = human umbilical vein-derived endothelial cells; NO = nitric oxide; TNF-α = tumor necrosis factor-α; IL-1β = interleukin-1β.
390892.fig.001