Value of C-Reactive Protein as a Risk Factor for Acute Coronary Syndrome: A Comparison with Apolipoprotein Concentrations and Lipid Profile

Table 1

Baseline characteristics of the study participants.

Parameter	ACS patients (𝑛=220)	Control group (𝑛=116)	P
Age (years)	64 ± 12	52 ± 9	0.01
TC (mmol/L)	4.96 (4.11–5.99)	4.75 (4.26–5.09)	0.024
LDL-C (mmol/L)	3.18 (2.35–3.93)	2.79 (2.3–3.15)	0.002
HDL-C (mmol/L)	1.16 ± 0.31	1.45 ± 0.31	<0.0001
Non-HDL-C (mmol/L)	3.85 (3.1–4.65)	3.2 (2.79–3.54)	<0.0001
TG (mmol/L)	1.3 (0.99–1.89)	0.92 (0.71–1.88)	<0.0001
TC : HDL-C	4.43 (3.72–5.42)	3.23 (2.82–3.72)	<0.0001
TG : HDL-C	2.77 (1.88–4.08)	1.47 (0.99–2.08)	<0.0001
LDL-C : HDL-C	2.77 (2.16–3.55)	1.85 (1.56–2.27)	<0.0001
apoA-I (g/L)	1.27 ± 0.24	1.41 ± 0.31	<0.0001
apoB (g/L)	0.81 (0.65–1.00)	0.72 (0.61–0.86)	0.0009
apoB : apoA-I	0.64 (0.52–0.8)	0.51 (0.45–0.62)	<0.0001
hsCRP (mg/L)	2.79 (1.12–6.08)	0.69 (0.36–1.35)	<0.0001
BMI (kg/m^2)	26.8 (24.5–29.8)	24.4 (22.1–27.7)	0.014
Women	41% (91)	53% (61)	<0.05
Men	59% (129)	47% (55)
Dyslipidemia	87% (191)	57% (66)	<0.00001
Hypertension	74% (163)	20% (23)	<0.00001
Diabetes mellitus	26% (57)	0	<0.00001
Smoking	54% (119)	27% (31)	0.0001
Family history of premature CAD	35% (77)	26% (30)	ns
Prior statin use	69% (152)	5% (6)	<0.0001

ACS: acute coronary syndrome; apoA-I: apolipoprotein A-I; apoB: apolipoprotein B; apoB : apoA-I: apolipoprotein B to apolipoprotein A-I ratio; BMI: body mass index; CAD: coronary artery disease; HDL-C: high-density lipoprotein cholesterol; hsCRP: high-sensitivity C-reactive protein; LDL-C: low-density lipoprotein cholesterol; LDL-C : HDL-C: low-density lipoprotein cholesterol to high-density lipoprotein cholesterol ratio; non-HDL-C: nonhigh-density lipoprotein cholesterol; TC: total cholesterol; TC : HDL-C: total cholesterol to high-density lipoprotein cholesterol ratio; TG: triglycerides; TG : HDL-C: triglycerides to high-density lipoprotein cholesterol ratio.