The Role of the Vagus Nerve: Modulation of the Inflammatory Reaction in Murine Polymicrobial Sepsis
Figure 5
The serum levels of corticosterone in sepsis are modulated by the vagus nerve. Vagotomy in the nonseptic organism does not influence the corticosterone level ( ng/mL). In polymicrobial sepsis, serum corticosterone is detected with ng/mL. In contrast, 24 h following CASP in vagotomised mice the corticosterone level is significantly increased up to ng/mL (*, Mann-Whitney, ).