Anti-Inflammatory Effects of Concentrated Ethanol Extracts of Edelweiss (Leontopodium alpinum Cass.) Callus Cultures towards Human Keratinocytes and Endothelial Cells
Figure 2
Effects of concentrated ethanol extract of Edelweiss callus cultures (ECC55) on UV-induced gene expression in cultured human keratinocytes. (a) Expression of inflammatory cytokine genes at 1 h and 24 h after irradiation with or without preincubation with ECC55 (25 μg/mL). (b) Expression of matrix metalloproteinases 9 and 1 genes (MMP9 and MMP1) as well as cyclooxygenase-2 gene (COX-2) at 1 h and 24 h after irradiation. Error bars in all figures correspond to S.D. *P < 0.05; †P < 0.01; ‡P < 0.001 versus control cells; §P < 0.05; #P < 0.01 versus UV-irradiated cells.
